Flashcards
Salmonella and Typhoid
Cards in this deck (15)
- 1ResevoirA human case or carrier
- 2TransmissionThrough contaminated food (can incubate for 7-14 days)
- 3SymptomsFever (20% mortalility) and complications- ulcers, meningitis
- 4Adherence to cellsType III Secretory system
- 5Macrophage InvasionUsed to enter lymph, where it can enter the blood
- 6Primary BacteraemiaWhere s.typhi enter the blood to infect other organs (i.e. the Gall Bladder)
- 7Secondary BacteremiaWhere bacteria leave the organs they have colonies to enter the blood again
- 8Cause of SymptomsSecondary Bacteremia
- 9Cause of CarrierBacteria have colonise the gall bladder but no symptoms are produced
- 10Salmonella Pathogenicity IslandAllows s.typhi to avoid Toll Like Receptors
- 11V.ICapsule protein that protects it from TLR4
- 12TV.IInhibits flagelling expression, that protects from TLR5
- 13S. typhi Resistance in the Gall BladderCan bind to gall stones, forming a biofilm and preventing antibiotic removal
- 14Intracellular MultiplicationHides in the gall bladder epithelium and multiplies
- 15TreatmentAntibiotics (and possible gall bladder removal)
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- Medical Microbiology (G.I Tract Infections) Flashcards on Salmonella and Typhoid, created by gina_evans0312 on 01/03/2014.
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- gina_evans0312
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