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aggression: serotonin
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- 1A01: serotonin-serotonin, in normal levels, exerts a calming, inhibitory effect on neuronal firing in the brain.
- low levels of serotonin, particularly in the pre-frontal cortex, remove this inhibitory effect with the consequence that individuals are less able to control their impulsive aggressive behaviour - 2A01: amygdala- normally, serotonin works in the frontal areas of the brain to inhibit firing of the amygdala, the part of the brain that controls fear, anger and other emotional responses.
-however, if there is less serotonin in these frontal areas, there is less inhibition of the amygdala.
-as a result, more likely to cause the person to act on their impulses and making aggression more likely - 3A02: mann et al (1990)-levels of serotonin were manipulated
-Mann et al (1990) administered dexfenfluramine to 35 healthy adult volunteers. Dexfenfluramine is a drug that depletes levels of serotonin in the brain. The findings were that males, but not females, exhibited greater levels of hostility and aggression after taking the drug. - 4A02: brown et al (1982)-the major metabolite (waste product) of serotonin tends to be low in the cerebrospinal fluid of poeple who display aggressive behaviour.
- the lack of waste products associated with the breakdown of serotonin is an indirect indication of low levels of serotonin in many aggressive individuals - 5A02: Rosado et al (2010)-took blood samples from 80 dogs referred to vetinery hospitals because of their aggressive behaviour towards humans.
-they compared these samples with blood samples taken from non-aggressive dogs.
-the aggressive dogs averaged 278 units of testosterone, while the non-aggressive dogs averaged 387 units of serotonin - 6IDA: RWA-if aggressive behaviour is a product of decreased levels of serotonin on the brain, then it should be possible to treat.
-SSRI antidepressant drugs increase the amount of serotonin available in the synapse.
-these are successfully used to treat aggressive children.
Ghaziuddin and Alessi (1992) found that administration of the antidepressant trazadone produced a notable improvement in about half the children treated - 7—
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- A2 Aggression Fichas sobre aggression: serotonin, creado por Veton Vishka el 17/02/2016.
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- Veton Vishka
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